New face care routine and challenge with MEG 21 products

Combating glycation and skin damage with my new skincare routine.

New face care routine with MEG 21 products

I have not been happy with my face care regimen of late. The dry weather, coupled with heavy anti-acne treatment and a bit of air-travel, has led to flaky, but still oily skin. Worst of all, lack of sleep and all the stress have ruined my under-eye area. The flakes look worse under foundation despite moisturiser, so it is time to change things around and go in for a new skincare routine.
Just as excess sugar is harmful for the body, it is also damaging to the skin. The sugar molecules bind to the elastin and collagen proteins in the skin, in a process called glycation. This leads to the formation of harmful free-radicals and proteins, oxidative stress and damaged skin. Supplamine, a molecule proven to counter the harmful effects of glycation, was actually developed during laboratory research on diabetes! And, I am now testing out a range of skincare products with Supplamine as the key ingredient.

Read more about the MEG 21 range of skincare products and my new face care routine below. 



Supplamine is made of two aminos - the first synthesises collagen and elastin, which keep skin elastic and youthful. The second inhibits the formation of the post-glycation proteins. The ingredient has undergone seven independent clinical trials so far, all of which have shown that Supplamine nullifies the toxic sugars (which cause signs of ageing) in the skin.
Developed by Dr Annette Tobia, a post-doctoral fellow from Rockerfeller University, NY, and her team, the MEG 21 range of skincare products is made by Dynamis Skin Science Inc. Dr Tobia's research focused on the impact of glycated sugar on the skin.
I have to finish a pile of journal articles and research reports about what this ingredient does, and what I have read so far has convinced me to change my face care regimen to incorporate Supplamine.

Here are the MEG 21 products in my new skincare routine:
  1. Refine and Refresh Moisturising Toner
  2. Cell Therapy Antioxidant Boost
  3. Smooth Radiance Face Treatment
  4. Bright and Firm Eye Treatment
New face care routine with MEG 21 products


From March 15, this is what my skincare routine is like:

  • Cleansing with Neutrogena's Oil-Free Acne Wash and the Konjac Sponge in the mornings; a wipe, followed by Burt's Bees Soap Bark and Chamomile Deep Cleansing Cream and the Foreo Luna in the evenings.
  • Refine and Refresh Toner
  • Antioxidant Boost
  • Smooth Radiance Face Treatment
  • Bright and Firm Eye Treatment
  • For the mornings, I follow up with primer and the rest of my makeup; in the evenings, I apply benzoyl peroxide over my acne once the moisturiser sinks in. 

As a rule, I don't use toners. They dry out my skin badly and cause flaking and breakouts. The Refine and Refresh clearly says it is a moisturising toner, so I am giving it a go for the next six weeks. It smells sweet and herbal.
The eye cream is super-creamy and is drunk up almost immediately by my super-dry under-eye area.
The Antioxidant Boost is a lightweight serum that reminds me a lot of Lancome Advanced Genefique, which is my HG serum.
So far, I have had signs of one new breakout coming out on the right cheek and some existing acne, but Auntie Flo is almost here; maybe that is why.

According to the literature, it takes four weeks for the Supplamine to act on glycated skin and to reduce redness, fine lines and wrinkles and to show smoother skin, better tone and firmness. I am going to stick to this regimen for the next few weeks.
Now this is what my acne (and oily skin) looks like right now. Ole Spotty-Face. Enid Blyton's favourite name for her villains.
New face care routine with MEG 21 products

And this is how my under-eye area looks after a few months of terrible sleep. Dark circle - check. Dry as a... desert - check. Tiny zit - check. Lines - check.
New face care routine with MEG 21 products

I will do a follow-up with after- photographs and republish these before- photos alongside, once I give the MEG 21 products a decent trial.

So in 28 days, I will see results. Tell you what, let's give the whole regimen a month and a half - we are halfway through March and I doubt I'll blog on April 14th or 15th since I'm celebrating my birthday, plus my Gramps has promised to go along with me on a crocodile-inhabited river trail in April. It will also be interesting to see how the products work when the weather becomes more humid. I will post the results of the challenge and follow-up during the last couple of days of April or the first couple of days in May, depending on my schedule.

Stay tuned for my review-and-results post by the first week of May.


  1. I can't wait to check out the results! My bags have bags lol What's sleep anyway?!

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  2. I don't even notice your dark under eye circles because your eye makeup is so pretty. I hope to see positive results from these products.

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  3. Sleep... I used to be familiar with that word until I went to Uni. Now I have no idea what it means.

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  4. I don't see dark circles under your eyes either. I have been using MEG 21 Bright & Firm for several months and I like it a lot!

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  5. I have never tried Meg 21, and can't wait to hear what you think about the results after you have used the line longer!

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  6. I have the same problem, my under-eye area looks terrible. :/ Haven't found a product that really helps yet.

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  7. I've been using the toner and serum and have been quite happy with them although I don't think I've seen any drastic results.

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  8. I've never heard of meg21! Thanks for introducing me.

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  9. This sounds interesting and something that I may want to try. I like an anti-aging (for prevention) and I do have adult acne issues. I need that moisturizing because my retinol dries the crud out of my face! I can't wait to see the results

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  10. "My bags have bags" lolol. True story. Anybody wanna trade?! XD But seriously, this stuff sounds highly promising. Looking forward to the outcome!

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  11. Sounds like it might be worth investigating.

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  12. Oh my gosh... the packaging alone on this makes me swoon over it... it's so spring like. I love to see results that are great and so quick to see. I have not heard of this product before... or the line, but I really enjoyed learning about it :)

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  13. Looking forward to seeing your results! Skin care is one of those things that really does take time to see a difference, so I hope you find some relief for your under eyes! My favorite hydrating eye cream is the Origins Eye Doctor!

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  14. This is a new brand to me. I am looking forward to your update.

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  15. Can't wait to read your sequel. I wanna know the results for sure.

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  16. I hope it works for you! And get some sleep! Lol

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  17. I'm curious about the toner. I typically don't use them for the same reason so I'll be interested to hear the results!

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  18. I have their toner and love it!

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  19. I'm kind of digging the simple packaging!

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  20. I haven't heard of this brand before. Looking forward to seeing your results.

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  21. I hope so too! Thank you! That's the IT Cosmetics concealer, so it hides the dark circles nicely.

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  22. Which means the concealer is working LOL. I hope the eye cream works for me as well!

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  23. Will definitely do an update!

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  24. I'm beginning to think sleep is the only answer :(

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  25. I'm liking the serum and the eye cream a lot so far!

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  26. Thanks very much! I love the packaging as well!

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  27. I have to try Origins Skin Doctor. You have AMAZING skin. Really! I'd love to find products that give me skin like yours!

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  28. I can't wait to see results either!

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  29. Sleep. What's that? Hang on, I need to find a dictionary... and it's 4 a.m.

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  30. I hope it works for me too!

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